Artane
DESCRIPTION

Artane is a brand name of a drug a commonly known as Trihexyphenidyl used to treat Parkinson’s disease. This medication is available in the form of tablets as well as elixirs. Artane belongs to the group of drugs called Anticholinergics; ingredients that interfere with Acetylcholine.

How It Works

Acetylcholine is a chemical found in the brain. It is also called a neurotransmitter as it aids in carrying messages from one brain cell to another. Your body requires a balance between Acetylcholine and Dopamine; another neurotransmitter for the control of muscle movement. The Dopamine level of persons taking anti-psychotic medication usually decreases. Artane works by impeding the effects of Acetylcholine to maintain the balance between Dopamine and Acetylcholine.

Uses

Poor muscle control in persons with Parkinson’s disease is what Artane is prescribed to treat. It is also used to treat side effects such as muscle stiffness and spasms caused by the intake of anti-psychotic medication.

Dosage

Follow the exact directions given by your doctor when taking Artane. Use the given measuring cup or spoon to get the correct dose.

The starting dose for adults with Parkinson’s disease is 1 mg per day. Increments of 2 mg can be made within 3 to 5 days. 6 to 10 mg is the usual daily dosage thereafter.

For children between 2 to 17 years of age, the initial dose is 0.1 or 0.2 mg/kg per day. It has to be given in 3 divided doses for a week. In the second week, the dose can be increased up to 0.05 to 0.3 mg/kg per day. The maximum daily dose that can be given to a child is 0.75 mg/kg.

Side Effects

Listed below are some of the common side effects of Artane.

Dry mouth
Drowsiness
Constipation
Difficulty in urinating
Nausea
Blurred Vision
Anxiety
Decreased sweating
Abdominal pain
Difficulty in swallowing

Some of the more serious side effects are:

Allergic reactions such as difficulty in breathing and swelling of face and throat area.
Seizures
Fainting
Fever
Rapid/slow heartbeat
Skin rashes
Hyperactivity
Hallucinations

If any of these serious side effects are experienced, seek medical attention immediately.

Another side effect of the intake of Artane is the reduced production of Saliva. As a consequence, you might develop tooth and gum problems.

Precautions

This medication must not be taken if you have certain medical conditions such Narrow-angle glaucoma, Ulcers or Bowel obstruction.

Be certain to inform your doctor if you have confronted any of the following health problems:

Heart diseases
Epilepsy
Depression
Kidney Disease
Liver Disease
Enlargement of the prostrate
Asthma
High/low blood pressure
Hyperthyroidism
Diabetes

Avoid being in heated places or under the sun for too long when taking this medication. It can overheat your body that might cause a heat stroke (Hyperthermia). Also, avoid consuming alcohol when taking Artane. Alcohol can react with this drug inside your body.

Provide prescriptions of any other drug you may be taking around the same time when you consult your doctor.

Self- Care

As Artane can cause blurred vision, be mindful when you are driving or working with sharp tools and other equipment.

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